Bioanalysis and PK
Accelera offers a full range of bioanalytical and pharmacokinetic services for drug discovery and development. A validated LIMS system (Watson) is used to manage all operations from sample tracking to data analysis, allowing the integrated design, conduct and reporting of bioanalytical and PK studies.
Method Development and Validation
Provision of a suitable bioanalytical method is an essential prerequisite for any pharmacokinetic study. LC-MS-MS methods can be developed extremely rapidly for discovery support, while further development and refinement required prior to formal validation.
Clinical and Preclinical Bioanalysis:
Synthesis of isotopically labelled internal standards
Parent compound and metabolites (2H, 13C, 18O)
Parmacokinetic Analysis
Accelera offers a full range of bioanalytical and pharmacokinetic services for drug discovery and development. A validated LIMS system (Watson) is used to manage all operations from sample tracking to data analysis, allowing the integrated design, conduct and reporting of bioanalytical and PK studies.
Method Development and Validation
Provision of a suitable bioanalytical method is an essential prerequisite for any pharmacokinetic study. LC-MS-MS methods can be developed extremely rapidly for discovery support, while further development and refinement required prior to formal validation.
Clinical and Preclinical Bioanalysis:
- State-of-the-art LC-MS-MS instrumentation
- Rapid turnaround bioanalysis for Phase I Clinical Studies
- Fast method development for discovery support
- Facilities for light-sensitive and cytotoxic compounds
- Automated sample handling
Synthesis of isotopically labelled internal standards
Parent compound and metabolites (2H, 13C, 18O)
Parmacokinetic Analysis
- WinNonLin®
- WinNonMix®
- NonMEM®Watson™
- Physiology-Based Pharmacokinetics (PBPK)
- Population Pharmacokinetics
- PK/PD modelling
© Accelera | Credits | Terms of use